JANUARY         14

Sean Eddy (Howard Hughes Medical Institute)

HMMER:  A New Generation of Homology Search Software

                          21

William Kaelin (Dana-Farber Cancer Institute, Howard Hughes Medical Institute)

The von Hippel-Lindau Tumor Suppressor Gene:  Insights into Oxygen Sensing and Cancer

                          28

FEBRUARY        4

Thomas Zwaka (Baylor College of Medicine)

Embryonic Stem Cells:  Building Alternative Pluripotency Networks 

                          11

Hugo Bellen (Baylor College of Medicine, Howard Hughes Medical Institute)

Growth Cone Guidance Receptors and the Pathogenesis of ALS/Lou Gehrig’s Disease

                          18

Magda Konarska (Rockefeller University)

Spliceosome Dynamics and Their Impact on the Fidelity of Splice Site Selection

                          25

David Morgan (University of California-San Francisco)

Finishing the Cell Cycle

MARCH              4

Karolin Luger (Colorado State University, Howard Hughes Medical Institute)

Posttranslational Modifications as Regulators of Chromatin Structure and Histone Chaperone Function

                          11

Hold for speaker to be hosted by Crossroads

                          18

Bruce Edgar (Fred Hutchinson Cancer Research Center)

Gut Homeostasis Mediated by Drosophila Intestinal Stem Cells

                          25

Michele Calos (Stanford University)

Harnessing Phage Integrases for Gene Therapy and Cell Therapy

APRIL                 1

John Rawls (University of North Carolina)

Host-microbe Relationships in the Zebrafish Digestive Tract

                            8

Ken Zaret (Fox Chase Cancer Center)

Connecting Inductive Signals to Epigenetics during Endoderm Differentiation

                          15

4:00 p.m.

Janet Rossant (The Hospital for Sick Children, Canada)

Making the Blastocyst:  Early Lineage Development in the Mouse

                          22

Leslie Loew (University of Connecticut Health Center)

The Virtual Cell Project 

                          29

Bing Ren (Ludwig Institute for Cancer Research)

Chromatin Signatures of Transcriptional Enhancers

MAY                    6

Geoff Rosenfeld (University of California-San Diego, Howard Hughes Medical Institute)

Life, Death, and Transformation:  Repeats, ncRNAs, and Architectural Strategies

                          13

Freda Miller (The Hospital for Sick Children, Canada)

Skin-derived Precursors:  From Morphogenesis to Repair

                          20

Michael Dyer (St. Jude Children’s Research Hospital)

The Role of the Rb Family in Retinal Development and Retinoblastoma